2018
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Conferences:
Poster presentation: The 10th International Conference of Modification, Degradation and Stabilization of Polymers (MoDeSt2018), Tokyo, Japan, 2-6 September 2018, Sericin Particles Loaded with Antineoplastic Agents for Cancer Management
Authors: Catalin Zaharia, Ionut Radu, Ariana Hudita, Bianca Galateanu, Eugenia Vasile (Tanasa), Paul Stanescu, Horia Iovu
Oral presentation:
Workshop - MoDaSyS Workshop 2018, AlgoNano: Algorithmic and Computational Methods in Bio-Medicine and Nanotechnology, Polymeric nanoparticles for drug delivery systems. Past, present and future perspectives
Author: Catalin Zaharia
ISI Articles:
Ionut Cristian Radu, Eugeniu Vasile, Celina Maria Damian, Horia Iovu, Paul Octavian Stanescu, Catalin Zaharia, Influence of the double bond LDH clay on the exfoliation/intercalation mechanism of polyacrylamide nanocomposite hydrogels, Materiale Plastice, 55(3), 2018, pp. 263-268.
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An important activity of disseminating the results was also the partner IECHIM. In the I / 2018 stage, the following dissemination actions were carried out in the form of oral communications or poster communications at international conferences, with remarkable visibility, for accomplishing the deliverables from the implementation plan and for presenting the obtained results:
1. “COMPOSITE NANOGELS FOR CONTROLLED DRUG DELIVERY” - ZAHARIA Anamaria, SPATARELU Catalina Paula, RADU Anita-Laura, CURSARU Bogdan, IORDACHE Tanta-Verona, FLOREA Ana-Mihaela, SANDU Teodor, TRICA Bogdan, SARBU Andrei, TEODORESCU Mircea, PERRIN François-Xavier - International Symposium Priorities of Chemistry for Sustainable Development PRIOCHEM - editia XIV , Bucharest, 10 - 12 October 2018.
2. NEW CANDIDATES FOR CONTROLLED DRUG DELIVERY BASED ON POLYETHYLENEGLYCOL DIACRYLATE AND NANOZEOLITE COMPOSITE NANOGELS, Anamaria Zaharia, Catalina Paula Spatarelu, Anita-Laura Radu, Bogdan Cursaru, Tanta-Verona Iordache, Ana-Mihaela Florea, Bogdan Trica, Andrei Sarbu, Mircea Teodorescu, Vlad Tofan, François-Xavier Perrin; A- XXXV-a National Chemistry Conference, perioada 02-05 October 2018, Caciulata, Valcea, Romania.
Also, the new researcher participated at the International Symposium PRIOCHEM Chemistry Priorities - XIV Edition, Bucharest, October 10-12, 2018, having an oral presentation entitled “BIOBUTANOL RECOVERY FROM ABE MIXTURE USING DISTILLATION COLUMNS”, COJOCARU Crina-Thea, GIJIU Luminita Cristiana, SARBU Andrei.
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2019
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21st Romanian International Conference on Chemistry and Chemical Engineering RICCCE21, which took place in Mamaia (Constanta), Romania from September 4-7, 2019.
1. Presented work:
Silk fibroin nanocarriers for the targeted delivery of 5-FU in cancer therapy
oral presentation
Authors: Elena-Alexandra Istratoiu, Ionut-Cristian Radu, Catalin Zaharia, Ariana Hudita, Bianca Galateanu, Eugenia Tanasa, Anca Hermenean, Horia Iovu
held on 06.09.2019, time interval 18.25-18.35 within section 6 New Materials and Nanomaterials.
2. Presented work:
Nanohydrogels platforms for drug delivery systems by self-assembly of hydrophilic polymers
oral presentation
Authors: Andreea Ion, Ionut-Cristian Radu, Catalin Zaharia, Ariana Hudita, Bianca Galateanu, Eugenia Tanasa, Horia Iovu
held on 06.09.2019, time interval 16.20-16.30 within section 6 New Materials and Nanomaterials.
An important activity for disseminating the results was also partnered by ICECHIM. In the second phase of 2019, the following dissemination actions were carried out in the form of oral or poster communications in international conferences, with remarkable visibility: 1 article accepted and published , which presents the researches that were the basis of the project activities (Benchmarking) and 4 participants in the form of oral communications or poster communications in international conferences, with remarkable visibility:
ISI article
B. Cursaru, A.-L. Radu, F.-X. Perrin, A. Sarbu, M. Teodorescu, A.-M. Gavrila, C.-M. Damian, T. Sandu, T.-V. Iordache, A. Zaharia *, Poly (ethylene glycol) Composite Hydrogels with Natural Zeolite as Filler for Controlled Delivery Applications, Macromolecular Research (IF = 1,758)
International conferences
1. "Innovative ligand-free nanogel structures capable of recognizing and retaining phospholipase A2 from bee venom"; Anamaria Zaharia, Răzvan Edward Botez, Crina Thea Cojocaru, Tanta-Verona Iordache, Andrei Sarbu, Celina Maria Damian, Ana-Mihaela Gavrila, Anita-Laura Radu, Teodor Sandu, Mircea Teodorescu; World Congress on Functional Materials and Nanotechnology, May 13-14, 2019, Valencia, Spain.
2. “A new generation of ligand-free nanogels capable of recognizing and retaining phospholipase A2 from bee venom” C.-T. Cojocaru, A. Zaharia, R. E. Botez, T.-V. Iordache, A. Sarbu, C. M. Damian, A.-L. Radu, A.-M. Gavrila, T. Sandu, M. Teodorescu; Graduate Student Symposium on Molecular Imprinting Berlin, Germany, August 28-August 30, 2019.
3. “NANOGELES COMPOSITES FOR CONTROLLED-DRUG DELIVERY”; Răzvan Edward Botez, Anamaria Zaharia, Anita-Laura Radu, Crina Thea Cojocaru, Tanta-Verona Iordache, Catalin Zaharia, Ionut Cristian Radu, Ana-Mihaela Gavrila, Teodor Sandu, Monica Duldner, Andrei Sarbu. 9th International Conference of the Chemical Societies of the South-East European Countries, May 5 - May 11, 2019, Targoviste, Romania.
4. "Advances in hydrogels and micro / nanohydrogels and their applications", COJOCARU Crina-Thea, BOTEZ Razvan Edward, ZAHARIA Anamaria, RADU Anita-Laura, SARBU Andrei, IORDACHE Tanta-Verona, GAVRILA Ana-Mihaela, SANDU Teodor, TEODORESCU Mirodu . NeXT - TRANS-SECTOR INNOVATIVE TECHNOLOGIES, May 7, 2019, Bucharest, Romania
Dissemination activity partner P3 (UMF Iasi)
The experimental results within the project were disseminated as follows:
International conference
L. Verestiuc, Mucoadhesive polymeric biomaterials - advantages, challenges and in vitro models for testing, International Seminar on Biomaterials and Regenerative Medicine (BioReMed 2019), September 26-27, 2019, Craiova, Romania (Plenary Speaker)
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2020
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The patent application entitled: 3D platform with controlled release for cancer therapy was filed with the State Office for Inventions and Trademarks (OSIM), authors: Catalin Zaharia, Ionut-Cristian Radu, Eugenia Tanasa, Paul-Octavian Stanescu, Bianca Galateanu, Marieta Costache, Ariana Hudita, Anamaria Zaharia having the number A / 00732 from 16.11.2020.
The UMF Iasi partner participated in the dissemination of the results obtained within the projects as follows:
Publish articles at ISI conferences:
1. IA Duceac, A. Lobiuc, S. Coseri and L. Verestiuc, "Tunable Hydrogels based on Chitosan, Collagen and Poly (Acrylic Acid) for Regenerative Medicine," 2019 E-Health and Bioengineering Conference (EHB), Iasi, Romania , pp. 1-4, doi: 10.1109 / EHB47216.2019.8969886 - published January 27, 2020
2. F. Turbatu, O. Aioanei, V. Balan, FD Cojocaru, M. Butnaru and L. Verestiuc, "A Perfusion Protocol for the Porcine Heart Decelularization with Application in Tissue Engineering," 2019 E-Health and Bioengineering Conference (EHB ), Iasi, Romania, pp. 1-4, doi: 10.1109 / EHB47216.2019.8969935 - published January 27, 2020.
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2020
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During stage IV, the coordinator of the UPB project together with the partner 1 UB managed to send an article for review in a magazine listed by ISI on the topic of this project. This article was accepted for publication in June 2021.
ISI article:
A. Hudita, I.C. Radu, B. Galateanu, O. Ginghina, H. Herman, C. Balta, M. Rosu, C. Zaharia, M. Costache, E. Tanasa, K. Velonia, A. Tsatsakis, A. Hermenean, Bioinspired silk fibroin nano -delivery systems protect against 5-FU induced gastrointestinal mucositis in a mouse model and display antitumor effects on HT-29 colorectal cancer cells in vitro, Nanotoxicology, accepted, in press, 2021, IF 4.925, Q1.
Also, one of the people employed as a doctoral student (new employee, Andreea-Cristina Ion) participated in an international conference with a poster paper (oral presentation 5 minutes).
Papers and conference participations:
Andreea Cristina Ion, Ionut-Cristian Radu, Bianca Galateanu, Eugenia Tanasa, Horia Iovu, Catalin Zaharia, Silk Fibroin Self-Assembled Architectures Loaded With Anti-neoplastic Drug for Cancer Therapy, Young Scientist Flash Presentation, Bucharest Polymer Conference (BPC2021), 2021 , Bucharest, Romania, poster presentation.